Tanya

 

 

 

 

TANYA'S

COMPREHENSIVE GUIDE TO

FELINE CHRONIC KIDNEY DISEASE

24 July 2000 - 24 July 2022

Please note that all payments are made in US dollars and

are not tax deductible since I am a private individual

 

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DIALYSIS

 

ON THIS PAGE:


What is Dialysis?


Haemodialysis


Peritoneal Dialysis


Continuous Renal Replacement Therapy


Enteric Dialysis


 

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Just Diagnosed? What You Need to Know First


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WHAT IS CKD?


What Happens in CKD


Causes of CKD


How Bad is It?


Is There Any Hope?


Acute Kidney Injury


 

KEY ISSUES: PROLONGING LIFE


Phosphorus Control


Hypertension

(High Blood Pressure)


Proteinuria


Anaemia


Potassium Imbalances


Pyelonephritis (Kidney Infections) and Urinary Tract Infections NEW


Metabolic Acidosis


Kidney Stones


 

KEY ISSUES: HELPING YOUR CAT FEEL BETTER


Nausea, Vomiting, Appetite Loss and Excess Stomach Acid


Maintaining Hydration


The B Vitamins (Including Methylcobalamin)


Constipation


 

CAT FOOD DATA


Ways of Assessing Food Content, Including What is Dry Matter Analysis


How to Use the Food Data Tables


USA Canned Food Data


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USA Food Data Book


 

SUPPORT


Coping with CKD


Tanya's Support Group


Success Stories


 

SYMPTOMS


Important: Crashing


Alphabetical List of Symptoms and Treatments


Fluid and Urinary  Imbalances (Dehydration, Overhydration and Urinary Issues)


Waste Product Regulation Imbalances (Vomiting, Appetite Loss, Excess Stomach Acid, Gastro-intestinal Problems, Mouth Ulcers Etc.)


Phosphorus and Calcium Imbalances


Miscellaneous Symptoms (Pain, Hiding Etc.)


 

DIAGNOSIS: WHAT DO ALL THE TEST RESULTS MEAN?


Early Detection


Blood Chemistry: Kidney Function, Potassium, Other Tests (ALT, Amylase, (Cholesterol, Etc.)


Calcium, Phosphorus, Parathyroid Hormone (PTH) and Secondary Hyperparathyroidism


Complete Blood Count (CBC): Red and White Blood Cells: Anaemia and Infection


Urinalysis (Urine Tests)


Other Tests: Ultrasound, Biopsy, X-rays etc.


Renomegaly (Enlarged Kidneys)


Which Tests to Have and Frequency of Testing


Factors that Affect Test Results


Normal Ranges


International and US Measuring Systems


 

TREATMENTS


Which Treatments are Essential


Fluid and Urinary Issues (Fluid Retention, Infections, Incontinence, Proteinuria)


Waste Product Regulation (Mouth Ulcers, GI Bleeding, Antioxidants, Adsorbents, Azodyl, Astro's CRF Oil)


Phosphorus, Calcium and Secondary Hyperparathyroidism (Calcitriol)


Phosphorus Binders


Steroids, Stem Cell Transplants and Kidney Transplants


Antibiotics and Painkillers


Holistic Treatments (Including Slippery Elm Bark)


ESAs (Aranesp, Epogen etc.) for Severe Anaemia


General Health Issues in a CKD Cat: Fleas, Arthritis, Dementia, Vaccinations


Tips on Medicating Your Cat


Obtaining Supplies Cheaply in the UK, USA and Canada


Working with Your Vet and Recordkeeping


 

DIET & NUTRITION


Nutritional Requirements of CKD Cats


The B Vitamins (Including Methylcobalamin)


What to Feed (and What to Avoid)


Persuading Your Cat to Eat


2007 Food Recall USA


 

FLUID THERAPY


Oral Fluids


Intravenous Fluids


Subcutaneous Fluids


Tips on Giving Subcutaneous Fluids


How to Give Subcutaneous Fluids with a Giving Set


How to Give Subcutaneous Fluids with a Syringe


Subcutaneous Fluids - Winning Your Vet's Support


Dialysis


 

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Polycystic Kidney Disease (PKD)


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Home > Fluid Therapy > Dialysis

 


Overview


  • When they first receive the CKD diagnosis, many people who are keen to do all they can to help their cat consider dialysis.

  • Unfortunately, ongoing dialysis is not appropriate for cats as it is for humans.

  • It is also only available in a limited number of centres, and is incredibly expensive — it costs up to US$25,000 for 2-3 weeks — so is beyond the reach of most people.


What is Dialysis?


 

The kidneys filter waste products from the blood, and discard them in urine. Damaged CKD kidneys cannot perform this function properly, so waste products build up in the bloodstream and make the patient feel unwell. Dialysis is a method of filtering the blood to remove the waste products so the patient feels better. Normally dialysis has to be performed on an ongoing basis.

 

There are two main types of dialysis, haemodialysis and peritoneal dialysis. Because of the cost and stress factor, neither type is commonly performed on cats, although haemodialysis is sometimes used to keep a seriously ill cat going prior to a kidney transplant, and peritoneal dialysis is occasionally used for cats with acute kidney injury.

 

A limited number of centres also offer a method called continous renal replacement therapy (CRRT).

 


Haemodialysis


 

This is the type of dialysis which people usually think of when they hear the word "dialysis". It is available for cats at a limited number of facilities, and, as in human patients, the process lasts several hours and has to be performed several times a week. It can only be given in hospital and is extremely expensive, with the Animal Medical Center in New York estimating the cost at US$20-25,000 for the first 2-3 weeks.  

 

One member of Tanya's CKD Support Group had haemodialysis performed on her cat in February and March 2017, prior to a kidney transplant. Her cat had the dialysis catheter implanted under anaesthesia and his dialysis sessions lasted around six hours. The goal is apparently to halve the kidney values each time; they will then increase again between sessions but hopefully will remain lower overall than at the beginning. The cat required some blood transfusions (not every cat on dialysis will need these), and medication for low blood pressure, which can be a side effect of dialysis. He received dialysis five times over a period of two weeks, but was able to maintain without further dialysis for a couple of weeks until he received his transplant.

 

If your cat does for whatever reason require ongoing dialysis, you will need very deep pockets. In September 2022 a member of Tanya's CKD Support Group called a number of facilities offering feline dialysis and was quoted a price of US$1000-2000 per treatment.

 

Nephrology Knowledge is owned by Dr Cathy Langston, a veterinary dialysis expert. She explains more about how haemodialyis is performed.

 

Intermittent hemodialysis for small animals (2011) Bloom CA & Labato MA Veterinary Clinics of America Small Animal Practice 41(1) pp115-133 discusses the use of haemodialysis.

 

Long-term outcome of cats and dogs with acute kidney injury treated with intermittent haemodialysis: 135 cats (1997-2010) (2012) Eatroff AE, Langston CE, Chalhoub S, Poeppel K & Mitelberg E Journal of the American Veterinary Medical Association 241(11) pp1471-8 discusses the benefits of dialysis. It concludes "Although there was a high mortality rate prior to hospital discharge, those patients that survived to discharge had a high probability of long-term survival."

 

Veterinary Partner has some information about haemodialysis for pets.

 

Availability


Ohio State University College of Veterinary Medicine mentions that "Only 22 veterinary hospitals in the U.S. and 40 worldwide offer dialysis services."

 

American Society of Veterinary Nephrology and Urology has a list of hospitals throughout the world where haemodialysis is available.

 

Intermittent hemodialysis for small animals (2011) Bloom CA & Labato MA Veterinary Clinics of America Small Animal Practice 41(1) pp115-133 has a list (current in 2011) of haemodialysis facilities worldwide.

 

University of California at Davis School of Veterinary Medicine explains more about haemodialysis, which it can provide.

 

University of Pennsylania School of Veterinary Medicine offers information and provides haemodialysis.

 

Ohio State University College of Veterinary Medicine reports on the successful treatment of a cat given haemodialysis in 2016 at Ohio State.

 

The Royal Veterinary College in the UK offers haemodialysis.

 


Peritoneal Dialysis


 

This entails using the peritoneal cavity as a means of dialysis. The peritoneum is semi-permeable, so urea/BUN, creatinine and phosphorus can pass through it. In peritoneal dialysis, a sterile dialysis solution is introduced into the peritoneal cavity, and this solution then collects waste products and excess electrolytes by means of diffusion. However, it is very hard to maintain sterility and avoid infection using this method, so it is highly unlikely that you will come across this form of treatment in practice; it tends to be reserved for cases of acute kidney injury

 

Peritoneal dialysis in cats with acute kidney injury: 22 cases (2001-2006) (2011) Cooper RL & Labato MA Journal of Veterinary Internal Medicine 25(1) examines the use of peritoneal dialysis in cats with acute kidney injury.

 

Management of acute renal failure in cats using peritoneal dialysis: a retrospective study of six cases (2003-2007) (2009) Dorval P & Boysen SR Journal of Feline Medicine & Surgery 11(2) pp107-115, found that peritoneal dialysis greatly helped five of the six cats with acute kidney injury.

 

Peritoneal dialysis in dogs and cats: 27 cases (1976-87) (1989) Crisp MS, Chew DJ, DiBartola SP & Birchard SJ Journal of the American Veterinary Medical Association 195(9) pp 1262-6 reports on the success rates of peritoneal dialysis in dogs and cats.

 

Availability


American Society of Veterinary Nephrology and Urology has a list of hospitals throughout the world where peritoneal dialysis is available.

 


Continuous Renal Replacement Therapy (CRRT)


 

Continous renal replacement therapy is used for acute situations when a cat is critically ill. It provides continous treatment and is usually only provided until the cat is stable once again, at which point the cat would often switch to haemodialysis.

 

Acute kidney injury in cats: part three - management (2014) Finch N Veterinary Times haas a photo (page 10) of a cat undergoing CRRT and intermittent haemodialysis.

 

Management of acute kidney injury with continuous venovenous haemodiafiltration in a cat 2015) Stanzani G, Jepson RE & Chan DL Journal of Feline Medicine and Surgery 17(6) pp551-556 reports on a cat who received CRRT in the UK.

 

Continous renal replacement therapy in dogs and cats (2011) Acierno MJ Veterinary Clinics of North America Small Animal Practice 41(1) pp135-146 discusses the use of CRRT.

 

Availability


American Society of Veterinary Nephrology and Urology has a list of hospitals throughout the world where CRRT is available.

 

Ontario Veterinary College offers CRRT in Canada.

 

The Royal Veterinary College offers CRRT in the UK.

 


Enteric Dialysis


 

This is not a standard form of dialysis, though its goals are similar. It is a method of trying to relieve the load on damaged kidneys by expelling waste via the gastrointestinal tract. Nutritional management of renal disease: an evidence-based approach (2014) Sanderson SL Today's Veterinary Practice 4(1) pp51-56 explains the theory behind enteric dialysis.

 

There is more information about enteric dialysis on the Nutritional Requirements page.

 

 

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This page last updated: 05 March 2023

 

Links on this page last checked: 05 March 2023

 

 

 

   

*****

 

TREATING YOUR CAT WITHOUT VETERINARY ADVICE CAN BE EXTREMELY DANGEROUS.

 

I have tried very hard to ensure that the information provided in this website is accurate, but I am NOT a vet, just an ordinary person who has lived through CKD with three cats. This website is for educational purposes only, and is not intended to be used to diagnose or treat any cat. Before trying any of the treatments described herein, you MUST consult a qualified veterinarian and obtain professional advice on the correct regimen for your cat and his or her particular requirements; and you should only use any treatments described here with the full knowledge and approval of your vet. No responsibility can be accepted.

 

If your cat appears to be in pain or distress, do not waste time on the internet, contact your vet immediately.

 

*****

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